Most industrial machinery mechanics work in factories or powerplants or at construction sites. Most are employed full time during regular business hours. However, mechanics may be on call or assigned to work nights or weekends. Overtime is common.

Industrial machinery mechanics suffer common injuries, such as cuts, bruises, and strains. They also may work in awkward positions, including on top of ladders or in cramped conditions under large machinery. To avoid injuries, they must follow safety precautions and wear protective equipment such as hardhats, safety glasses, steel-tipped shoes, and hearing protectors. Even so, they experience rates of injuries and illnesses that are much higher than the national average.